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New York/US - September 29, 2026 - Protheragen has advanced its integrated microneedle technology solutions, delivering endâtoâend custom services including formulation development and material selection & characterization for pharmaceutical enterprises, cosmetic companies, and related industry partners. The service portfolio covers multiple mainstream microneedle formats, including coated microneedle development, dissolving microneedle, hollow microneedle, hydrogelâforming microneedle, and solid microneedle, to satisfy diversified transdermal drug delivery demands for smallâmolecule compounds, proteins, nucleic acids, and other active substances.
Microneedle technology is an innovative transdermal drug delivery system that employs micronâscale needles to pierce the stratum corneum and deliver therapeutic agents to targeted skin depths to join local microcirculation. By bypassing gastrointestinal digestion and firstâpass metabolism, this technology improves drug bioavailability, enables localized therapy to lower systemic adverseâreaction risks, and supports sustained or controllable drug release through structural tuning of microneedle arrays.
Within its fullâscope microneedle technology solutions, Protheragen offers specialized coated microneedle development services for surfaceâloaded delivery systems. Coated microneedles feature solid sharp substrates covered by drugâcontaining soluble coating layers; once inserted into skin, interstitial fluid dissolves excipients in coatings, releasing payloads into target tissues. Protheragen supports multiple coating approaches, including masked dip coating, inkjet printing, immersion coating and, spray coating. Its service portfolio includes coatingâformulation development, microneedle geometric design, coatingâmaterial screening, process optimization, delivery performance evaluation, and safety compatibility assessment, to secure uniform drug distribution, preserved drug bioactivity, and expected release profiles.
Meanwhile, the dissolving microneedle platform constitutes another core offering under Protheragen’s service suite. Dissolving microneedles embed active pharmaceutical ingredients within biodegradable polymer matrices. After skin application, the whole needle body dissolves completely inside tissue, generating no sharp biohazard waste and enabling painâfree selfâadministration. Protheragen leverages PDMSâmoldâbased fabrication workflows, together with a broad selection of matrix materials such as carboxymethyl chitosan, PVP, PVA, and PLGA. Its dissolving microneedle services span structural design, prototyping, formulation optimization, analytical testing covering mechanical strength, dissolution kinetics, and biocompatibility, as well as regulatory document support for clients from the pharmaceutical and cosmetic sectors.
Backed by crossâdisciplinary teams of scientists and engineers, Protheragen’s microneedle technology services run through the whole R&D pipeline: initial concept design, prototype preparation, material characterization, formulation optimization, preclinical and clinical evaluation, manufacturing scaleâup, and postâcommercialization technical support. Protheragen maintains collaborative links with global pharmaceutical firms, medicalâdevice manufacturers, and research institutes to keep pace with cuttingâedge microneedle research progress.
About Protheragen
Protheragen provides comprehensive, tailorâmade drug delivery development services for various advanced delivery technologies, supporting partners to overcome technical bottlenecks in drug permeability, stability, and administration mode. Whether clients are in the pharmaceutical industry, medical research, or a related field, its team of experts is ready to support researchers’ novel drug delivery development needs.
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Company Name: Protheragen
Contact Person: Hannah Green
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Country: United States
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